Hi, thank you for this useful method! For the Hi-C file, could you please briefly the megamap Hi-C is? I suppose it's not the same as the average Hi-C used by ABC model?
We have not trained powerlaw models. If you don't have cell specific hic, opt to use megamap hic instead: https://s3.us-central-1.wasabisys.com/aiden-encode-hic-mirror/bifocals_iter2/tissues.hic. Megamap is a culmination of hic across many different tissues.