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Add utility functions for adding additional variables to a NONMEM dataset (TAD, etc.) #33

@mccarthy-m-g

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@mccarthy-m-g

Here's an existing function I wrote that we can tidy/adapt. One thing to decide is whether we should do this in run_eval() or leave it as a function the user could apply to their NONMEM data set if they need it. The former is probably better, since it allows us to assume TAD is always available.

add_time_after_dose <- function(nonmem_data) {
  nonmem_data |>
    dplyr::group_by(ID, OCC) |>
    dplyr::mutate(
      TDOSE = dplyr::if_else(AMT > 0 | EVID == 1 | EVID == 4, TIME, NA),
      DOSEEND = TDOSE + LENGTH
    ) |>
    tidyr::fill(TDOSE, DOSEEND) |>
    dplyr::mutate(
      TAD = TIME - TDOSE,
      TAI = dplyr::if_else(AMT == 0 | EVID == 0 | EVID == 2, TIME - DOSEEND, 0),
      .after = RATE
    ) |>
    dplyr::select(-TDOSE, -DOSEEND) |>
    dplyr::ungroup()
}

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