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-
-For the paper:
-
-Kremer Y, Leger JF, Goodman D, Brette R, Bourdieu L (2011) Late
-emergence of the vibrissa direction selectivity map in the rat barrel
-cortex. J Neurosci 31:10689-700
-
-Abstract
-
-In the neocortex, neuronal selectivities for multiple sensorimotor
-modalities are often distributed in topographical maps thought to
-emerge during a restricted period in early postnatal
-development. Rodent barrel cortex contains a somatotopic map for
-vibrissa identity, but the existence of maps representing other
-tactile features has not been clearly demonstrated. We addressed the
-issue of the existence in the rat cortex of an intrabarrel map for
-vibrissa movement direction using in vivo two-photon imaging. We
-discovered that the emergence of a direction map in rat barrel cortex
-occurs long after all known critical periods in the somatosensory
-system. This map is remarkably specific, taking a pinwheel-like form
-centered near the barrel center and aligned to the barrel cortex
-somatotopy. We suggest that this map may arise from intracortical
-mechanisms and demonstrate by simulation that the combination of
-spike-timing-dependent plasticity at synapses between layer 4 and
-layer 2/3 and realistic pad stimulation is sufficient to produce such
-a map. Its late emergence long after other classical maps suggests
-that experience-dependent map formation and refinement continue
+## For the paper:
+
+Kremer Y, Leger JF, Goodman D, Brette R, Bourdieu L (2011) Late
+emergence of the vibrissa direction selectivity map in the rat barrel
+cortex. *J Neurosci* 31:10689-700
+
+## Abstract
+
+In the neocortex, neuronal selectivities for multiple sensorimotor
+modalities are often distributed in topographical maps thought to
+emerge during a restricted period in early postnatal
+development. Rodent barrel cortex contains a somatotopic map for
+vibrissa identity, but the existence of maps representing other
+tactile features has not been clearly demonstrated. We addressed the
+issue of the existence in the rat cortex of an intrabarrel map for
+vibrissa movement direction using in vivo two-photon imaging. We
+discovered that the emergence of a direction map in rat barrel cortex
+occurs long after all known critical periods in the somatosensory
+system. This map is remarkably specific, taking a pinwheel-like form
+centered near the barrel center and aligned to the barrel cortex
+somatotopy. We suggest that this map may arise from intracortical
+mechanisms and demonstrate by simulation that the combination of
+spike-timing-dependent plasticity at synapses between layer 4 and
+layer 2/3 and realistic pad stimulation is sufficient to produce such
+a map. Its late emergence long after other classical maps suggests
+that experience-dependent map formation and refinement continue
throughout adult life.
Brian simulator models are available at this web page:
-http://briansimulator.org/docs/examples-frompapers_Kremer_et_al_2011.html
+[http://briansimulator.org/docs/examples-frompapers_Kremer_et_al_2011.html](http://briansimulator.org/docs/examples-frompapers_Kremer_et_al_2011.html)
The simulation creates a selectivity map similar to Fig. 7c middle:
-
+
and a histogram of the angles present:
-
+
-This simulation requires Brian which can be downloaded and installed
-from the instructions available at http://www.briansimulator.org/
+This simulation requires Brian which can be downloaded and installed
+from the instructions available at [http://www.briansimulator.org/](http://www.briansimulator.org/)
-For support on installing and using Brian simulations there is a
-support group at https://groups.google.com/group/briansupport.
-
+For support on installing and using Brian simulations there is a
+support group at [https://groups.google.com/group/briansupport](https://groups.google.com/group/briansupport).
+
+---
+
+2025-07-09: Converted README to Markdown.