From 49acbe25bf74779192a5b8a36fe508bd154473ea Mon Sep 17 00:00:00 2001 From: EnfxcFCb6 Date: Wed, 9 Jul 2025 16:14:42 -0400 Subject: [PATCH 1/2] Standardized README to Markdown format --- index.html => README.md | 72 +++++++++++++++++++++-------------------- 1 file changed, 37 insertions(+), 35 deletions(-) rename index.html => README.md (60%) diff --git a/index.html b/README.md similarity index 60% rename from index.html rename to README.md index df3c0d3..70c1f6d 100644 --- a/index.html +++ b/README.md @@ -1,47 +1,49 @@ -
-For the paper:
-
-Kremer Y, Leger JF, Goodman D, Brette R, Bourdieu L (2011) Late
-emergence of the vibrissa direction selectivity map in the rat barrel
-cortex. J Neurosci 31:10689-700
-
-Abstract
-
-In the neocortex, neuronal selectivities for multiple sensorimotor
-modalities are often distributed in topographical maps thought to
-emerge during a restricted period in early postnatal
-development. Rodent barrel cortex contains a somatotopic map for
-vibrissa identity, but the existence of maps representing other
-tactile features has not been clearly demonstrated. We addressed the
-issue of the existence in the rat cortex of an intrabarrel map for
-vibrissa movement direction using in vivo two-photon imaging. We
-discovered that the emergence of a direction map in rat barrel cortex
-occurs long after all known critical periods in the somatosensory
-system. This map is remarkably specific, taking a pinwheel-like form
-centered near the barrel center and aligned to the barrel cortex
-somatotopy. We suggest that this map may arise from intracortical
-mechanisms and demonstrate by simulation that the combination of
-spike-timing-dependent plasticity at synapses between layer 4 and
-layer 2/3 and realistic pad stimulation is sufficient to produce such
-a map. Its late emergence long after other classical maps suggests
-that experience-dependent map formation and refinement continue
+# For the paper:
+
+Kremer Y, Leger JF, Goodman D, Brette R, Bourdieu L (2011) Late  
+emergence of the vibrissa direction selectivity map in the rat barrel  
+cortex. *J Neurosci* 31:10689-700
+
+## Abstract
+
+In the neocortex, neuronal selectivities for multiple sensorimotor  
+modalities are often distributed in topographical maps thought to  
+emerge during a restricted period in early postnatal  
+development. Rodent barrel cortex contains a somatotopic map for  
+vibrissa identity, but the existence of maps representing other  
+tactile features has not been clearly demonstrated. We addressed the  
+issue of the existence in the rat cortex of an intrabarrel map for  
+vibrissa movement direction using in vivo two-photon imaging. We  
+discovered that the emergence of a direction map in rat barrel cortex  
+occurs long after all known critical periods in the somatosensory  
+system. This map is remarkably specific, taking a pinwheel-like form  
+centered near the barrel center and aligned to the barrel cortex  
+somatotopy. We suggest that this map may arise from intracortical  
+mechanisms and demonstrate by simulation that the combination of  
+spike-timing-dependent plasticity at synapses between layer 4 and  
+layer 2/3 and realistic pad stimulation is sufficient to produce such  
+a map. Its late emergence long after other classical maps suggests  
+that experience-dependent map formation and refinement continue  
 throughout adult life.
 
 Brian simulator models are available at this web page:
 
-http://briansimulator.org/docs/examples-frompapers_Kremer_et_al_2011.html
+[http://briansimulator.org/docs/examples-frompapers_Kremer_et_al_2011.html](http://briansimulator.org/docs/examples-frompapers_Kremer_et_al_2011.html)
 
 The simulation creates a selectivity map similar to Fig. 7c middle:
 
-screenshot1
+![screenshot1](./screenshot1.png)
 
 and a histogram of the angles present:
 
-screenshot2
+![screenshot2](./screenshot2.png)
 
-This simulation requires Brian which can be downloaded and installed
-from the instructions available at http://www.briansimulator.org/
+This simulation requires Brian which can be downloaded and installed  
+from the instructions available at [http://www.briansimulator.org/](http://www.briansimulator.org/)
 
-For support on installing and using Brian simulations there is a
-support group at https://groups.google.com/group/briansupport.
-
+For support on installing and using Brian simulations there is a +support group at [https://groups.google.com/group/briansupport](https://groups.google.com/group/briansupport). + +--- + +2025-07-09: Converted README to Markdown. \ No newline at end of file From 4a7aa4dc13c5c59021b71c5ed7c68d9f9b79511c Mon Sep 17 00:00:00 2001 From: rsakai Date: Thu, 10 Jul 2025 15:53:32 -0400 Subject: [PATCH 2/2] Update README.md --- README.md | 48 ++++++++++++++++++++++++------------------------ 1 file changed, 24 insertions(+), 24 deletions(-) diff --git a/README.md b/README.md index 70c1f6d..e74fd74 100644 --- a/README.md +++ b/README.md @@ -1,29 +1,29 @@ -# For the paper: +## For the paper: -Kremer Y, Leger JF, Goodman D, Brette R, Bourdieu L (2011) Late -emergence of the vibrissa direction selectivity map in the rat barrel +Kremer Y, Leger JF, Goodman D, Brette R, Bourdieu L (2011) Late +emergence of the vibrissa direction selectivity map in the rat barrel cortex. *J Neurosci* 31:10689-700 ## Abstract -In the neocortex, neuronal selectivities for multiple sensorimotor -modalities are often distributed in topographical maps thought to -emerge during a restricted period in early postnatal -development. Rodent barrel cortex contains a somatotopic map for -vibrissa identity, but the existence of maps representing other -tactile features has not been clearly demonstrated. We addressed the -issue of the existence in the rat cortex of an intrabarrel map for -vibrissa movement direction using in vivo two-photon imaging. We -discovered that the emergence of a direction map in rat barrel cortex -occurs long after all known critical periods in the somatosensory -system. This map is remarkably specific, taking a pinwheel-like form -centered near the barrel center and aligned to the barrel cortex -somatotopy. We suggest that this map may arise from intracortical -mechanisms and demonstrate by simulation that the combination of -spike-timing-dependent plasticity at synapses between layer 4 and -layer 2/3 and realistic pad stimulation is sufficient to produce such -a map. Its late emergence long after other classical maps suggests -that experience-dependent map formation and refinement continue +In the neocortex, neuronal selectivities for multiple sensorimotor +modalities are often distributed in topographical maps thought to +emerge during a restricted period in early postnatal +development. Rodent barrel cortex contains a somatotopic map for +vibrissa identity, but the existence of maps representing other +tactile features has not been clearly demonstrated. We addressed the +issue of the existence in the rat cortex of an intrabarrel map for +vibrissa movement direction using in vivo two-photon imaging. We +discovered that the emergence of a direction map in rat barrel cortex +occurs long after all known critical periods in the somatosensory +system. This map is remarkably specific, taking a pinwheel-like form +centered near the barrel center and aligned to the barrel cortex +somatotopy. We suggest that this map may arise from intracortical +mechanisms and demonstrate by simulation that the combination of +spike-timing-dependent plasticity at synapses between layer 4 and +layer 2/3 and realistic pad stimulation is sufficient to produce such +a map. Its late emergence long after other classical maps suggests +that experience-dependent map formation and refinement continue throughout adult life. Brian simulator models are available at this web page: @@ -38,12 +38,12 @@ and a histogram of the angles present: ![screenshot2](./screenshot2.png) -This simulation requires Brian which can be downloaded and installed +This simulation requires Brian which can be downloaded and installed from the instructions available at [http://www.briansimulator.org/](http://www.briansimulator.org/) -For support on installing and using Brian simulations there is a +For support on installing and using Brian simulations there is a support group at [https://groups.google.com/group/briansupport](https://groups.google.com/group/briansupport). --- -2025-07-09: Converted README to Markdown. \ No newline at end of file +2025-07-09: Converted README to Markdown.