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+
-I am an Assistant Professor in the Psychology Department, Bioengineering Department, and Center for Cognitive and Brain Health at Northeastern University and a Research Affiliate in the Radiology & Biomedical Imaging Department in the Yale School of Medicine creating computational and statistical tools for precision neuroscience research. My use of "precision neuroscience" is intended to invoke both measurement theory and precision medicine concepts.
+The Neuroscience Precision Research & Idiographic Statistical Methods (NeuroPRISM) Lab, led by Dr. Stephanie Noble in the Institute for Cognitive and Brain Health at Northeastern University, creates computational and statistical tools for precision neuroscience research. Our use of "precision neuroscience" is intended to invoke both measurement theory and precision medicine concepts.
-My research aims to use fundamental measurement principles and individual-centered methods to advance brain-behavior understanding and prediction. To set the stage for this research program, I have developed approaches to improve detection of brain-behavior relationships based on my work characterizing measurement and signal properties. Furthermore, I have a longstanding commitment to providing best practices for machine learning and big data analysis, especially for predicting psychiatric and developmental outcomes. The overarching motivation for these goals is one that the field is growing to embrace: more precise inferential and predictive methods are needed to accelerate discovery in health and disease. Many neuroscience-related research areas have faced an explosion in the size and complexity of data and methods, and I aim to explore solutions to problems that span disciplines.
+We aim to use fundamental measurement principles and individual-centered methods to advance brain-behavior understanding and prediction. To set the stage for this research program, we have developed approaches to improve detection of brain-behavior relationships based on our work characterizing measurement and signal properties. Furthermore, we have a longstanding commitment to providing best practices for machine learning and big data analysis, especially for predicting psychiatric and developmental outcomes. The overarching motivation for these goals is one that the field is growing to embrace: more precise inferential and predictive methods are needed to accelerate discovery in health and disease. Many neuroscience-related research areas have faced an explosion in the size and complexity of data and methods, and we aim to explore solutions to problems that span disciplines.
-I previously completed my BSE in Chemical and Biological Engineering at Princeton University, my PhD in the Interdepartmental Neuroscience Program at Yale University with Dr. Todd Constable, and my Postdoctoral Research in the Radiology & Biomedical Imaging Department at the Yale School of Medicine with Dr. Dustin Scheinost.
-My experiences also extend beyond academia: before the PhD, I was co-founding Chief Scientific Officer of goBlue Labs (selected media and Craving to Quit product; now Mindsciences), and a consultant for Source Signal Imaging (now part of Cortech Solutions). I am currently a consultant for Elite Warrior Identification.
-
-Want to get in touch? I'm always open to new opportunities and collaborations—don't hesitate to contact me through any of the links below.
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+ Dr. Stephanie Noble is an Assistant Professor in the Department of Psychology, Department of Bioengineering, and Institute for Cognitive and Brain Health at Northeastern University where she focuses on creating tools to facilitate more precise human neuroscience inference and prediction. Her research lies at the intersection of data science, neuroscience, and open science. Specifically, her work has addressed open questions and introduced new paths forward to facilitate more reliable and valid neuroimaging studies, and paves a way towards improving individual-level models of behavior and disease. Previously, Dr. Noble received a BS in Chemical & Biological Engineering from Princeton University, a PhD in the Interdepartmental Neuroscience Program at Yale University, and completed Postdoctoral training in Radiology & Biomedical Imaging at Yale. Beyond academia, she co-founded EEG startup goBlue Labs and served a consultant for Source Signal Imaging (now part of Cortech Solutions) and Elite Warrior Identification. Dr. Noble’s work has been supported by a number of awards, including from the NSF and NIH, and her work has appeared in various journals including PNAS, Nature, and Neuron.
+
Curriculum Vitae
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+ Alex Fischbach is a sixth-year PhD candidate whose research focuses on measurement precision and data-driven method development for functional brain imaging (fMRI). She graduated from Providence College (PC) in 2017 with dual B.A. degrees in Psychology and Biology and a certificate in Neuroscience. During her undergraduate training, she conducted research at both PC and Brown University, investigating the neurobiological, environmental, and genetic antecedents of Body Dysmorphic Disorder and disorders of anxiety and fear. She earned her M.S. (2020–2023) while working with Dr. Lisa Feldman Barrett and Dr. Karen Quigley in the Interdisciplinary Affective Science Lab, where her research examined how brainstem and subcortical structures, traditionally associated with ‘fight-or-flight’ responses, support everyday cognitive functions such as working memory in the absence of threat. In the NeuroPRISM Lab, Alex is developing a scalable, Python-based artifact correction pipeline designed to identify and remove local physiological noise in deep brain regions, thereby enabling more precise and reliable estimates of neural activity in the subcortex.
++ Alex is expected to graduate in 2026 and is open to opportunities in both academia and industry. + To get in touch, please email her at alexkfischbach [at] gmail.com +
+
+ Hallee is a PhD student interested in test-retest reliability, naturalistic neuroimaging, precision psychiatry, and statistics. She received a Bachelor of Science in Behavioural Neuroscience in 2021, and a Master of Science in Neuroscience in 2023 - both from the University of British Columbia (UBC). During her time at UBC, she worked with Dr. Fidel Vila-Rodriguez at the Non-Invasive Neurostimulation Therapies (NINET) lab, where her interest in the use of fRMI for interventional psychiatry began. She then joined the Naturalistic Neuroimaging Lab with Dr. Tamara Vanderwal to explore how movie-fMRI could provide improvements in functional connectivity test-retest reliability for precision psychiatric applications. In the NeuroPRISM lab, Hallee is currently working on creating a tool for exploring expected effect sizes of typical fMRI studies.
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+ Fabricio Cravo is a Postdoctoral Researcher in the NeuroPRISM Lab specializing in computational and statistical analysis of fMRI data, particularly for more powerful study planning and inference. Dr. Cravo received his Master's degree in Computer Engineering from CentraleSupélec, France, with a specialization in AI, machine learning, and databases. He then completed his Ph.D. in Computer Science and Applied Mathematics at Paris-Saclay University (ranked #1 globally in Mathematics by ARWU, 2020-2023), where his research focused on distributed algorithms for microbiological systems and mathematical modeling of gene regulatory networks with continuous-time Markov and ordinary differential equations models. He is currently the lead developer of MobsPy, a programming language for biochemical reaction networks, and SHOCK, an empirical power MATLAB toolbox for fMRI studies that features optimized statistical algorithms.
+
Personal Website
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+ Boston Precision Brain & Mental Health Hack is a three-day event happening at Northeastern University this Fall designed as an extension to Brainhack Global. This event will bring together students, postdocs, and faculty to tackle precision medicine problems through hackathon-style projects, hands-on tutorials, and discussions. Following the Brainhack spirit, this hackathon is not a “coding sprint” or exclusive to programmers—neuroscientists, psychologists, engineers, programmers, students, faculty, and more can and do make a significant contribution to the event. Given some methodological overlap and goals, + we are excited to incorporate both digital health and neuroscience approaches. +
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+ + Any questions not covered by the FAQ? Contact us at: fischbach.a@northeastern.edu +
+ +| Time | +Session | +Location | +
|---|---|---|
| 9:30 AM | +Intro | +Curry Student Center | +
| 10:00 AM | +Project "speed dating" & Coffee | +Curry Student Center | +
| 11:00 AM | +Talk: Susan Whitfield-Gabrieli | +Curry Student Center | +
| 12:00 PM | +Lunch/ Finish "Speed dating" | +Curry Student Center | +
| 1:00 PM | +Talk: Don Robinaugh | +Curry Student Center | +
| 2:00 PM | +Open hacking | +Curry Student Center | +
| 4:00 PM | +Wrap up | +Curry Student Center | +
| Time | +Session | +Location | +
|---|---|---|
| 9:00 AM | +Open hacking | +Curry Student Center | +
| 9:30 AM | +Coffee & Open hacking | +Curry Student Center | +
| 10:00 AM | +Data blitz | +Curry Student Center | +
| 11:00 AM | +Open hacking | +Curry Student Center | +
| 12:00 PM | +Lunch | +Curry Student Center | +
| 1:30 PM onwards | +Open Hacking | +Egan Research Center room 440 | +
| Time | +Session | +Location | +
|---|---|---|
| 9:00 AM | +Open hacking | +Curry Student Center | +
| 9:30 AM | +Coffee & Open hacking | +Curry Student Center | +
| 10:00 AM | +Talk: Satrajit Ghosh: An Intelligent Infrastructure as a Foundation for Modern Science | +Curry Student Center | +
| 11:00 AM | +Talk: Paola Pedrelli: Rethinking Psychiatry: From Diagnoses to Mechanisms of Change and Biomarkers | +Curry Student Center | +
| 12:00 PM | +Lunch | +Curry Student Center | +
| 1:00 PM | +Open hacking | +Curry Student Center | +
| 3:00 PM | +Presentations & Wrap-up | +Curry Student Center | +
| 4:00 PM | +Social! | +TBH | +
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+ Curry Student Center - 2nd Floor suites
+360 Huntington Avenue, Boston, MA 02115
+ +Public Transit:
+Parking:
+Renaissance Garage (835 Columbus Ave)
+ +Egan Research Center, room 440
+120 Forsyth Street, Boston, MA 02115
+ +From Curry (10 min walk):
+Walk south to Ruggles St → Columbus Ave → Turn left to Egan Research Center
+ +Public Transit:
+Orange Line to Ruggles (5 min walk west on Columbus)
+ +To register, please click the following Google Form link:
+ +Are there any associated fees?
+No - this event is free.
+ +Are there any prerequisites to take part in any of the activities?
+No - there are no prerequisites.
+ +Why should I participate in a hackathon?
+Hackathons are a great way to learn new skills that will be useful in your everyday work as a researcher. Beyond that, hackathons are also an opportunity to meet, collaborate and exchange best practices with members of the community.
+ +Is there a registration deadline for the Brainhack?
+No. However, our event space has a strict capacity, so space is limited.
+ +Will this event have a virtual option?
+Yes. However, please note that in previous years over 95% of attendees have participated in person. Additionally, while we will do our best to actively monitor virtual streams, some event spaces are not equipped with cameras and/or microphones.
+ +Who should I reach out to if I have questions?
+Please email Alex Fischbach <fischbach.a@northeastern.edu>
+ + +How is this year's Brainhack different from previous years?
+This year, we are incorporating hackathon projects into the three-day schedule.
+ +What is a hackathon project?
+A project developed during the event, where participants work in teams to create a tool, analysis, experiment, or idea related to the hackathon's theme. Projects can range from coding and data analysis to designing workflows, visualizations, or community resources. The focus is on creativity, learning, and collaboration rather than polished end products or technical coding/programming skills.
+ +I don't want to submit/pitch a project, but I want to contribute. How does this work?
+At the hackathon, each project leader will pitch at the beginning of the event. Then you will have the possibility to chat with the project leaders before you decide which projects to join.
+ + +Who can submit a hackathon project?
+Anyone registered for Brainhack can submit a project to the project pool. It might be either a project you are already working on and would like help with or a completely new project you would like to start.
+ +Where can I find examples of previous brainhack projects?
++ To see brainhack project examples from prior hackathons, + click here. +
+ + +I want to submit a hackathon project. What information do you need?
+In this Google form there will be a section that asks you to provide: (1) the title of your project and (2) a description of your project (1-2 sentences).
+ +Does my project idea need to be fully formed?
+No! Brainhack projects are typically broad/general at the beginning, and then become more refined throughout the hackathon, as other collaborators contribute to the project.
+ +What is the deadline for project submission?
+We will close project submission before the Brainhack starts, but we recommend you send a draft submission earlier, if possible.
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+ + TBH +
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