diff --git a/docs/example_pairwise_comparisons.ipynb b/docs/example_pairwise_comparisons.ipynb
index 8f4ab69..d134784 100644
--- a/docs/example_pairwise_comparisons.ipynb
+++ b/docs/example_pairwise_comparisons.ipynb
@@ -16,10 +16,10 @@
"execution_count": 1,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:52:44.430148Z",
- "iopub.status.busy": "2024-12-02T19:52:44.430015Z",
- "iopub.status.idle": "2024-12-02T19:52:44.647935Z",
- "shell.execute_reply": "2024-12-02T19:52:44.647555Z"
+ "iopub.execute_input": "2024-12-13T20:58:24.149172Z",
+ "iopub.status.busy": "2024-12-13T20:58:24.148996Z",
+ "iopub.status.idle": "2024-12-13T20:58:24.639576Z",
+ "shell.execute_reply": "2024-12-13T20:58:24.639167Z"
},
"jukit_cell_id": "JlHVCFc6jg"
},
@@ -45,10 +45,10 @@
"execution_count": 2,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:52:44.649701Z",
- "iopub.status.busy": "2024-12-02T19:52:44.649507Z",
- "iopub.status.idle": "2024-12-02T19:52:44.652722Z",
- "shell.execute_reply": "2024-12-02T19:52:44.652420Z"
+ "iopub.execute_input": "2024-12-13T20:58:24.641172Z",
+ "iopub.status.busy": "2024-12-13T20:58:24.640979Z",
+ "iopub.status.idle": "2024-12-13T20:58:24.648286Z",
+ "shell.execute_reply": "2024-12-13T20:58:24.647986Z"
},
"jukit_cell_id": "KnQdvFxPkd"
},
@@ -72,10 +72,10 @@
"execution_count": 3,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:52:44.653983Z",
- "iopub.status.busy": "2024-12-02T19:52:44.653793Z",
- "iopub.status.idle": "2024-12-02T19:52:44.706713Z",
- "shell.execute_reply": "2024-12-02T19:52:44.706323Z"
+ "iopub.execute_input": "2024-12-13T20:58:24.649669Z",
+ "iopub.status.busy": "2024-12-13T20:58:24.649556Z",
+ "iopub.status.idle": "2024-12-13T20:58:24.755600Z",
+ "shell.execute_reply": "2024-12-13T20:58:24.755261Z"
},
"jukit_cell_id": "dlU1p2c9cE"
},
@@ -102,10 +102,10 @@
"execution_count": 4,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:52:44.708297Z",
- "iopub.status.busy": "2024-12-02T19:52:44.708140Z",
- "iopub.status.idle": "2024-12-02T19:52:44.721039Z",
- "shell.execute_reply": "2024-12-02T19:52:44.720758Z"
+ "iopub.execute_input": "2024-12-13T20:58:24.756964Z",
+ "iopub.status.busy": "2024-12-13T20:58:24.756808Z",
+ "iopub.status.idle": "2024-12-13T20:58:24.782573Z",
+ "shell.execute_reply": "2024-12-13T20:58:24.782268Z"
},
"jukit_cell_id": "gQ5lHlQ04X"
},
@@ -393,10 +393,10 @@
"execution_count": 5,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:52:44.745963Z",
- "iopub.status.busy": "2024-12-02T19:52:44.745676Z",
- "iopub.status.idle": "2024-12-02T19:52:44.748082Z",
- "shell.execute_reply": "2024-12-02T19:52:44.747780Z"
+ "iopub.execute_input": "2024-12-13T20:58:24.813376Z",
+ "iopub.status.busy": "2024-12-13T20:58:24.813222Z",
+ "iopub.status.idle": "2024-12-13T20:58:24.815733Z",
+ "shell.execute_reply": "2024-12-13T20:58:24.815308Z"
},
"jukit_cell_id": "ybX13ZBK8Q"
},
@@ -435,7 +435,7 @@
"jukit_cell_id": "6gx14BlSwz"
},
"source": [
- "## Compare between wells and siRNA treatments with the same concentration"
+ "## Compare between different wells and siRNA concentrations"
]
},
{
@@ -443,10 +443,10 @@
"execution_count": 6,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:52:44.749262Z",
- "iopub.status.busy": "2024-12-02T19:52:44.749084Z",
- "iopub.status.idle": "2024-12-02T19:53:08.806010Z",
- "shell.execute_reply": "2024-12-02T19:53:08.805601Z"
+ "iopub.execute_input": "2024-12-13T20:58:24.817376Z",
+ "iopub.status.busy": "2024-12-13T20:58:24.817198Z",
+ "iopub.status.idle": "2024-12-13T20:58:48.225778Z",
+ "shell.execute_reply": "2024-12-13T20:58:48.225233Z"
},
"jukit_cell_id": "CRa8vLBRj8"
},
@@ -469,10 +469,10 @@
"execution_count": 7,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:08.807845Z",
- "iopub.status.busy": "2024-12-02T19:53:08.807680Z",
- "iopub.status.idle": "2024-12-02T19:53:08.812868Z",
- "shell.execute_reply": "2024-12-02T19:53:08.812532Z"
+ "iopub.execute_input": "2024-12-13T20:58:48.227715Z",
+ "iopub.status.busy": "2024-12-13T20:58:48.227573Z",
+ "iopub.status.idle": "2024-12-13T20:58:48.233127Z",
+ "shell.execute_reply": "2024-12-13T20:58:48.232737Z"
},
"jukit_cell_id": "cGLOXfXNrN"
},
@@ -587,10 +587,10 @@
"execution_count": 8,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:08.814179Z",
- "iopub.status.busy": "2024-12-02T19:53:08.814037Z",
- "iopub.status.idle": "2024-12-02T19:53:08.816150Z",
- "shell.execute_reply": "2024-12-02T19:53:08.815814Z"
+ "iopub.execute_input": "2024-12-13T20:58:48.234569Z",
+ "iopub.status.busy": "2024-12-13T20:58:48.234289Z",
+ "iopub.status.idle": "2024-12-13T20:58:48.236737Z",
+ "shell.execute_reply": "2024-12-13T20:58:48.236350Z"
},
"jukit_cell_id": "qzMvL0c8sb"
},
@@ -614,10 +614,10 @@
"execution_count": 9,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:08.817405Z",
- "iopub.status.busy": "2024-12-02T19:53:08.817251Z",
- "iopub.status.idle": "2024-12-02T19:53:08.819387Z",
- "shell.execute_reply": "2024-12-02T19:53:08.819051Z"
+ "iopub.execute_input": "2024-12-13T20:58:48.238100Z",
+ "iopub.status.busy": "2024-12-13T20:58:48.237864Z",
+ "iopub.status.idle": "2024-12-13T20:58:48.240138Z",
+ "shell.execute_reply": "2024-12-13T20:58:48.239749Z"
},
"jukit_cell_id": "7modF1v2ll"
},
@@ -641,7 +641,7 @@
"jukit_cell_id": "ucjifXHnJI"
},
"source": [
- "## Compare between different siRNAs and Wells at the same concentrations"
+ "## Compare between different siRNAs and wells at the same concentrations"
]
},
{
@@ -649,10 +649,10 @@
"execution_count": 10,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:08.820624Z",
- "iopub.status.busy": "2024-12-02T19:53:08.820488Z",
- "iopub.status.idle": "2024-12-02T19:53:11.115742Z",
- "shell.execute_reply": "2024-12-02T19:53:11.115336Z"
+ "iopub.execute_input": "2024-12-13T20:58:48.241509Z",
+ "iopub.status.busy": "2024-12-13T20:58:48.241210Z",
+ "iopub.status.idle": "2024-12-13T20:58:50.438288Z",
+ "shell.execute_reply": "2024-12-13T20:58:50.437902Z"
},
"jukit_cell_id": "JPLwsPbVsU"
},
@@ -676,10 +676,10 @@
"execution_count": 11,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:11.117480Z",
- "iopub.status.busy": "2024-12-02T19:53:11.117341Z",
- "iopub.status.idle": "2024-12-02T19:53:11.122848Z",
- "shell.execute_reply": "2024-12-02T19:53:11.122493Z"
+ "iopub.execute_input": "2024-12-13T20:58:50.440204Z",
+ "iopub.status.busy": "2024-12-13T20:58:50.440051Z",
+ "iopub.status.idle": "2024-12-13T20:58:50.445450Z",
+ "shell.execute_reply": "2024-12-13T20:58:50.445122Z"
},
"jukit_cell_id": "lFR01EXVLC"
},
@@ -708,62 +708,62 @@
"
pearsons_correlation | \n",
" Metadata_Concentration__antehoc_group0 | \n",
" Metadata_Concentration__antehoc_group1 | \n",
- " Metadata_siRNA__posthoc_group0 | \n",
- " Metadata_siRNA__posthoc_group1 | \n",
" Metadata_Well__posthoc_group0 | \n",
" Metadata_Well__posthoc_group1 | \n",
+ " Metadata_siRNA__posthoc_group0 | \n",
+ " Metadata_siRNA__posthoc_group1 | \n",
" \n",
" \n",
" \n",
" \n",
" | 0 | \n",
- " 0.128001 | \n",
+ " -0.258292 | \n",
" 0.001 | \n",
" 0.001 | \n",
- " NF1 Target 1 | \n",
- " NF1 Target 2 | \n",
+ " E10 | \n",
" F10 | \n",
- " G10 | \n",
+ " Scramble | \n",
+ " NF1 Target 1 | \n",
"
\n",
" \n",
" | 1 | \n",
- " 0.190290 | \n",
+ " -0.011791 | \n",
" 0.001 | \n",
" 0.001 | \n",
+ " E10 | \n",
+ " F4 | \n",
+ " Scramble | \n",
" NF1 Target 1 | \n",
- " NF1 Target 2 | \n",
- " F10 | \n",
- " G4 | \n",
"
\n",
" \n",
" | 2 | \n",
- " 0.173737 | \n",
+ " 0.188021 | \n",
" 0.001 | \n",
" 0.001 | \n",
+ " E10 | \n",
+ " F7 | \n",
+ " Scramble | \n",
" NF1 Target 1 | \n",
- " NF1 Target 2 | \n",
- " F10 | \n",
- " G7 | \n",
"
\n",
" \n",
" | 3 | \n",
- " -0.258292 | \n",
+ " -0.045444 | \n",
" 0.001 | \n",
" 0.001 | \n",
- " NF1 Target 1 | \n",
- " Scramble | \n",
- " F10 | \n",
" E10 | \n",
+ " G10 | \n",
+ " Scramble | \n",
+ " NF1 Target 2 | \n",
"
\n",
" \n",
" | 4 | \n",
- " 0.089742 | \n",
+ " -0.081625 | \n",
" 0.001 | \n",
" 0.001 | \n",
- " NF1 Target 1 | \n",
+ " E10 | \n",
+ " G4 | \n",
" Scramble | \n",
- " F10 | \n",
- " E4 | \n",
+ " NF1 Target 2 | \n",
"
\n",
" \n",
"\n",
@@ -771,32 +771,32 @@
],
"text/plain": [
" pearsons_correlation Metadata_Concentration__antehoc_group0 \\\n",
- "0 0.128001 0.001 \n",
- "1 0.190290 0.001 \n",
- "2 0.173737 0.001 \n",
- "3 -0.258292 0.001 \n",
- "4 0.089742 0.001 \n",
+ "0 -0.258292 0.001 \n",
+ "1 -0.011791 0.001 \n",
+ "2 0.188021 0.001 \n",
+ "3 -0.045444 0.001 \n",
+ "4 -0.081625 0.001 \n",
"\n",
- " Metadata_Concentration__antehoc_group1 Metadata_siRNA__posthoc_group0 \\\n",
- "0 0.001 NF1 Target 1 \n",
- "1 0.001 NF1 Target 1 \n",
- "2 0.001 NF1 Target 1 \n",
- "3 0.001 NF1 Target 1 \n",
- "4 0.001 NF1 Target 1 \n",
+ " Metadata_Concentration__antehoc_group1 Metadata_Well__posthoc_group0 \\\n",
+ "0 0.001 E10 \n",
+ "1 0.001 E10 \n",
+ "2 0.001 E10 \n",
+ "3 0.001 E10 \n",
+ "4 0.001 E10 \n",
"\n",
- " Metadata_siRNA__posthoc_group1 Metadata_Well__posthoc_group0 \\\n",
- "0 NF1 Target 2 F10 \n",
- "1 NF1 Target 2 F10 \n",
- "2 NF1 Target 2 F10 \n",
- "3 Scramble F10 \n",
- "4 Scramble F10 \n",
+ " Metadata_Well__posthoc_group1 Metadata_siRNA__posthoc_group0 \\\n",
+ "0 F10 Scramble \n",
+ "1 F4 Scramble \n",
+ "2 F7 Scramble \n",
+ "3 G10 Scramble \n",
+ "4 G4 Scramble \n",
"\n",
- " Metadata_Well__posthoc_group1 \n",
- "0 G10 \n",
- "1 G4 \n",
- "2 G7 \n",
- "3 E10 \n",
- "4 E4 "
+ " Metadata_siRNA__posthoc_group1 \n",
+ "0 NF1 Target 1 \n",
+ "1 NF1 Target 1 \n",
+ "2 NF1 Target 1 \n",
+ "3 NF1 Target 2 \n",
+ "4 NF1 Target 2 "
]
},
"execution_count": 11,
@@ -813,10 +813,10 @@
"execution_count": 12,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:11.124166Z",
- "iopub.status.busy": "2024-12-02T19:53:11.124023Z",
- "iopub.status.idle": "2024-12-02T19:53:11.126142Z",
- "shell.execute_reply": "2024-12-02T19:53:11.125797Z"
+ "iopub.execute_input": "2024-12-13T20:58:50.446909Z",
+ "iopub.status.busy": "2024-12-13T20:58:50.446796Z",
+ "iopub.status.idle": "2024-12-13T20:58:50.448816Z",
+ "shell.execute_reply": "2024-12-13T20:58:50.448514Z"
},
"jukit_cell_id": "EiRceI8zqd"
},
@@ -840,10 +840,10 @@
"execution_count": 13,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:11.127483Z",
- "iopub.status.busy": "2024-12-02T19:53:11.127297Z",
- "iopub.status.idle": "2024-12-02T19:53:11.129395Z",
- "shell.execute_reply": "2024-12-02T19:53:11.129049Z"
+ "iopub.execute_input": "2024-12-13T20:58:50.450152Z",
+ "iopub.status.busy": "2024-12-13T20:58:50.450027Z",
+ "iopub.status.idle": "2024-12-13T20:58:50.451967Z",
+ "shell.execute_reply": "2024-12-13T20:58:50.451666Z"
},
"jukit_cell_id": "uHLGwABthL"
},
@@ -853,7 +853,7 @@
"output_type": "stream",
"text": [
"Output Dataframe Columns:\n",
- "['pearsons_correlation', 'Metadata_Concentration__antehoc_group0', 'Metadata_Concentration__antehoc_group1', 'Metadata_siRNA__posthoc_group0', 'Metadata_siRNA__posthoc_group1', 'Metadata_Well__posthoc_group0', 'Metadata_Well__posthoc_group1']\n"
+ "['pearsons_correlation', 'Metadata_Concentration__antehoc_group0', 'Metadata_Concentration__antehoc_group1', 'Metadata_Well__posthoc_group0', 'Metadata_Well__posthoc_group1', 'Metadata_siRNA__posthoc_group0', 'Metadata_siRNA__posthoc_group1']\n"
]
}
],
@@ -867,7 +867,7 @@
"jukit_cell_id": "K9KWpg6A7A"
},
"source": [
- "## Compare between different stains, conditions, and wells\n",
+ "## Compare between different siRNAs and wells at the same concentrations\n",
"Supplying the _drop_cols parameter excludes wells from the output dataframe, even though wells are used to compare groups."
]
},
@@ -876,10 +876,10 @@
"execution_count": 14,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:11.130698Z",
- "iopub.status.busy": "2024-12-02T19:53:11.130526Z",
- "iopub.status.idle": "2024-12-02T19:53:13.372280Z",
- "shell.execute_reply": "2024-12-02T19:53:13.371877Z"
+ "iopub.execute_input": "2024-12-13T20:58:50.453295Z",
+ "iopub.status.busy": "2024-12-13T20:58:50.453169Z",
+ "iopub.status.idle": "2024-12-13T20:58:52.612752Z",
+ "shell.execute_reply": "2024-12-13T20:58:52.612363Z"
},
"jukit_cell_id": "OHRc2Dyid6"
},
@@ -904,10 +904,10 @@
"execution_count": 15,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:13.374236Z",
- "iopub.status.busy": "2024-12-02T19:53:13.374071Z",
- "iopub.status.idle": "2024-12-02T19:53:13.378578Z",
- "shell.execute_reply": "2024-12-02T19:53:13.378233Z"
+ "iopub.execute_input": "2024-12-13T20:58:52.614565Z",
+ "iopub.status.busy": "2024-12-13T20:58:52.614438Z",
+ "iopub.status.idle": "2024-12-13T20:58:52.618560Z",
+ "shell.execute_reply": "2024-12-13T20:58:52.618237Z"
},
"jukit_cell_id": "rGAPBpItug"
},
@@ -941,33 +941,33 @@
" \n",
" \n",
" | 0 | \n",
- " 0.128001 | \n",
+ " -0.258292 | \n",
+ " E10 | \n",
" F10 | \n",
- " G10 | \n",
"
\n",
" \n",
" | 1 | \n",
- " 0.190290 | \n",
- " F10 | \n",
- " G4 | \n",
+ " -0.011791 | \n",
+ " E10 | \n",
+ " F4 | \n",
"
\n",
" \n",
" | 2 | \n",
- " 0.173737 | \n",
- " F10 | \n",
- " G7 | \n",
+ " 0.188021 | \n",
+ " E10 | \n",
+ " F7 | \n",
"
\n",
" \n",
" | 3 | \n",
- " -0.258292 | \n",
- " F10 | \n",
+ " -0.045444 | \n",
" E10 | \n",
+ " G10 | \n",
"
\n",
" \n",
" | 4 | \n",
- " 0.089742 | \n",
- " F10 | \n",
- " E4 | \n",
+ " -0.081625 | \n",
+ " E10 | \n",
+ " G4 | \n",
"
\n",
" \n",
"\n",
@@ -975,18 +975,18 @@
],
"text/plain": [
" pearsons_correlation Metadata_Well__posthoc_group0 \\\n",
- "0 0.128001 F10 \n",
- "1 0.190290 F10 \n",
- "2 0.173737 F10 \n",
- "3 -0.258292 F10 \n",
- "4 0.089742 F10 \n",
+ "0 -0.258292 E10 \n",
+ "1 -0.011791 E10 \n",
+ "2 0.188021 E10 \n",
+ "3 -0.045444 E10 \n",
+ "4 -0.081625 E10 \n",
"\n",
" Metadata_Well__posthoc_group1 \n",
- "0 G10 \n",
- "1 G4 \n",
- "2 G7 \n",
- "3 E10 \n",
- "4 E4 "
+ "0 F10 \n",
+ "1 F4 \n",
+ "2 F7 \n",
+ "3 G10 \n",
+ "4 G4 "
]
},
"execution_count": 15,
@@ -1003,10 +1003,10 @@
"execution_count": 16,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:13.379837Z",
- "iopub.status.busy": "2024-12-02T19:53:13.379697Z",
- "iopub.status.idle": "2024-12-02T19:53:13.381799Z",
- "shell.execute_reply": "2024-12-02T19:53:13.381472Z"
+ "iopub.execute_input": "2024-12-13T20:58:52.620308Z",
+ "iopub.status.busy": "2024-12-13T20:58:52.620133Z",
+ "iopub.status.idle": "2024-12-13T20:58:52.622432Z",
+ "shell.execute_reply": "2024-12-13T20:58:52.622116Z"
},
"jukit_cell_id": "zZHKZyRQcw"
},
@@ -1030,10 +1030,10 @@
"execution_count": 17,
"metadata": {
"execution": {
- "iopub.execute_input": "2024-12-02T19:53:13.383054Z",
- "iopub.status.busy": "2024-12-02T19:53:13.382878Z",
- "iopub.status.idle": "2024-12-02T19:53:13.384941Z",
- "shell.execute_reply": "2024-12-02T19:53:13.384609Z"
+ "iopub.execute_input": "2024-12-13T20:58:52.624091Z",
+ "iopub.status.busy": "2024-12-13T20:58:52.623907Z",
+ "iopub.status.idle": "2024-12-13T20:58:52.626160Z",
+ "shell.execute_reply": "2024-12-13T20:58:52.625845Z"
},
"jukit_cell_id": "8G7ZiPRvd8"
},