diff --git a/src/coreclr/vm/threadsuspend.cpp b/src/coreclr/vm/threadsuspend.cpp
index a060c121cb6874..671572fa1d6884 100644
--- a/src/coreclr/vm/threadsuspend.cpp
+++ b/src/coreclr/vm/threadsuspend.cpp
@@ -20,6 +20,8 @@
 #include "exinfo.h"
 #endif
 
+bool IsCallDescrWorkerInternalReturnAddress(PCODE pCode);
+
 #define HIJACK_NONINTERRUPTIBLE_THREADS
 
 bool ThreadSuspend::s_fSuspendRuntimeInProgress = false;
@@ -4597,6 +4599,19 @@ void Thread::HijackThread(ExecutionState *esb X86_ARG(ReturnKind returnKind) X86
     // Remember the place that the return would have gone
     m_pvHJRetAddr = *esb->m_ppvRetAddrPtr;
 
+#ifndef TARGET_X86
+    // Except for x86, no registers are scanned as part of the HijackFrame on top of the stack.
+    // This still allows scanning of the return value because the registers in question are
+    // scanned as part of the calling method's roots. The problem arises if we are returning to
+    // CallDescrWorkerInternal, which is hand written assembly with no GC info, so a returned
+    // objectref would be neither reported nor updated by a GC.
+    if (IsCallDescrWorkerInternalReturnAddress((PCODE)(TADDR)m_pvHJRetAddr))
+    {
+        STRESS_LOG2(LF_SYNC, LL_INFO100, "Thread::HijackThread(%p): Early out - return address %p is CallDescrWorkerInternal.\n", this, m_pvHJRetAddr);
+        return;
+    }
+#endif // !TARGET_X86
+
     IS_VALID_CODE_PTR((FARPROC) (TADDR)m_pvHJRetAddr);
     // TODO [DAVBR]: For the full fix for VsWhidbey 450273, the below
     // may be uncommented once isLegalManagedCodeCaller works properly