diff --git a/src/sentry/api/utils.py b/src/sentry/api/utils.py
index 3b4e4045e47a8c..16c102179cadc8 100644
--- a/src/sentry/api/utils.py
+++ b/src/sentry/api/utils.py
@@ -49,6 +49,7 @@
 from sentry.utils.sdk import capture_exception, merge_context_into_scope, set_span_attribute
 from sentry.utils.snuba import (
     DatasetSelectionError,
+    QueryBytesScannedExceeded,
     QueryConnectionFailed,
     QueryExecutionError,
     QueryExecutionTimeMaximum,
@@ -402,6 +403,11 @@ def handle_query_errors() -> Generator[None]:
         if isinstance(error, RateLimitExceeded):
             sentry_sdk.set_tag("query.error_reason", "RateLimitExceeded")
             raise Throttled(detail=RATE_LIMIT_ERROR_MESSAGE)
+        elif isinstance(error, QueryBytesScannedExceeded):
+            sentry_sdk.set_tag("query.error_reason", "QueryBytesScannedExceeded")
+            raise TimeoutException(
+                detail="Query has exceeded its bytes scanned limit. Please try your query with a smaller date range or fewer projects."
+            )
         if isinstance(
             error,
             (
diff --git a/src/sentry/utils/snuba.py b/src/sentry/utils/snuba.py
index e88baf3c044e18..c6df552ebc91f8 100644
--- a/src/sentry/utils/snuba.py
+++ b/src/sentry/utils/snuba.py
@@ -446,6 +446,14 @@ class QueryConnectionFailed(QueryExecutionError):
     """
 
 
+class QueryBytesScannedExceeded(QueryExecutionError):
+    """
+    The query exceeded the max_bytes_to_read limit set by an allocation policy.
+    This is a ClickHouse-level rejection (error code 307, TOO_MANY_BYTES),
+    distinct from Snuba-level rate limiting.
+    """
+
+
 clickhouse_error_codes_map = {
     10: QueryMissingColumn,
     43: QueryIllegalTypeOfArgument,
@@ -456,6 +464,7 @@ class QueryConnectionFailed(QueryExecutionError):
     241: QueryMemoryLimitExceeded,
     271: DatasetSelectionError,
     279: QueryConnectionFailed,
+    307: QueryBytesScannedExceeded,
 }