diff --git a/instrumentation/opentelemetry-instrumentation-genai-openai/examples/embeddings/requirements.txt b/instrumentation/opentelemetry-instrumentation-genai-openai/examples/embeddings/requirements.txt
index 40781e21..2174f3c4 100644
--- a/instrumentation/opentelemetry-instrumentation-genai-openai/examples/embeddings/requirements.txt
+++ b/instrumentation/opentelemetry-instrumentation-genai-openai/examples/embeddings/requirements.txt
@@ -1,4 +1,4 @@
-openai~=2.41.0
+openai~=2.43.0
 
 opentelemetry-sdk~=1.42.0
 opentelemetry-exporter-otlp-proto-grpc~=1.42.0
diff --git a/instrumentation/opentelemetry-instrumentation-genai-openai/examples/manual/requirements.txt b/instrumentation/opentelemetry-instrumentation-genai-openai/examples/manual/requirements.txt
index 7c1d660d..8649bc94 100644
--- a/instrumentation/opentelemetry-instrumentation-genai-openai/examples/manual/requirements.txt
+++ b/instrumentation/opentelemetry-instrumentation-genai-openai/examples/manual/requirements.txt
@@ -1,4 +1,4 @@
-openai~=2.41.0
+openai~=2.43.0
 
 opentelemetry-sdk~=1.42.0
 opentelemetry-exporter-otlp-proto-grpc~=1.42.0
diff --git a/instrumentation/opentelemetry-instrumentation-genai-openai/examples/zero-code/requirements.txt b/instrumentation/opentelemetry-instrumentation-genai-openai/examples/zero-code/requirements.txt
index d363e79f..8ceed672 100644
--- a/instrumentation/opentelemetry-instrumentation-genai-openai/examples/zero-code/requirements.txt
+++ b/instrumentation/opentelemetry-instrumentation-genai-openai/examples/zero-code/requirements.txt
@@ -1,4 +1,4 @@
-openai~=2.41.0
+openai~=2.43.0
 
 opentelemetry-sdk~=1.42.0
 opentelemetry-exporter-otlp-proto-grpc~=1.42.0
diff --git a/instrumentation/opentelemetry-instrumentation-genai-openai/tests/requirements.latest.txt b/instrumentation/opentelemetry-instrumentation-genai-openai/tests/requirements.latest.txt
index 574df695..ffaea6d1 100644
--- a/instrumentation/opentelemetry-instrumentation-genai-openai/tests/requirements.latest.txt
+++ b/instrumentation/opentelemetry-instrumentation-genai-openai/tests/requirements.latest.txt
@@ -37,7 +37,7 @@
 # This variant of the requirements aims to test the system using
 # the newest supported version of external dependencies.
 
-openai==2.41.1
+openai==2.43.0
 # older pydantic is required for PyPy < 3.11
 pydantic==2.12.5
 httpx==0.28.1