1.95 beta regression: "displacement ... is not within [-2147483648, 2147483647]"

[theemathas]

Regression found by the 1.95 beta crater run.

[INFO] [stdout] error: displacement 3614090360 is not within [-2147483648, 2147483647]
[INFO] [stdout]   --> src/main.rs:51:10
[INFO] [stdout]    |
[INFO] [stdout] 51 |         "lea {a:e}, [{a} + {r10} + 0xd76aa478]",
[INFO] [stdout]    |          ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
[INFO] [stdout]    |
[INFO] [stdout] note: instantiated into assembly here
[INFO] [stdout]   --> <inline asm>:13:10
[INFO] [stdout]    |
[INFO] [stdout] 13 | lea eax, [rax + r11 + 0xd76aa478]
[INFO] [stdout]    |          ^
[INFO] [stdout] 
[INFO] [stdout] 
[INFO] [stdout] error: displacement 3905402710 is not within [-2147483648, 2147483647]
[INFO] [stdout]   --> src/main.rs:62:10
[INFO] [stdout]    |
[INFO] [stdout] 62 |         "lea {d:e}, [{d} + {r10} + 0xe8c7b756]",
[INFO] [stdout]    |          ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
[INFO] [stdout]    |
[INFO] [stdout] note: instantiated into assembly here
[INFO] [stdout]   --> <inline asm>:22:10
[INFO] [stdout]    |
[INFO] [stdout] 22 | lea esi, [rsi + r11 + 0xe8c7b756]
[INFO] [stdout]    |          ^

(multiple similar errors omitted for brevity)

https://crater-reports.s3.amazonaws.com/beta-1.95-3/1.95.0-beta.3/gh/magniff.md5sum-rs-openssl/log.txt

[theemathas]

Minimal reproducer:

use std::arch::asm;
fn main() {
    unsafe {
        asm!(
            "lea {a:e}, [{a} + {r10} + 0xd76aa478]",
            a = out(reg) _,
            r10 = out(reg) _,
        );
    }
}

[theemathas]

Bisection result:

searched toolchains c40c51f9fdfa90b9c91c1601ec1442225c6b5c36 through 67aec36df76a7b67b71a8ee47684467e16f1847e


********************************************************************************
Regression in 466ea4e6c39f8a43727edcc726ca86b499e14d83
********************************************************************************

Attempting to search unrolled perf builds
ERROR: couldn't find perf build comment

Regressed in #150722. cc @nikic