Potential new test: f-I relationship based on Spoleti et al. 2022#69
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appukuttan-shailesh wants to merge 4 commits intoKaliLab:masterfrom
Open
Potential new test: f-I relationship based on Spoleti et al. 2022#69appukuttan-shailesh wants to merge 4 commits intoKaliLab:masterfrom
appukuttan-shailesh wants to merge 4 commits intoKaliLab:masterfrom
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Based on Fig. 5 of:
Spoleti, E., Krashia, P., La Barbera, L., Nobili, A., Lupascu, C. A., Giacalone, E., ... & D'Amelio, M. (2022). Early derailment of firing properties in CA1 pyramidal cells of the ventral hippocampus in an Alzheimer's disease mouse model. Experimental Neurology, 350, 113969.
Validation Framework Test Entries:
https://model-catalog.brainsimulation.eu/#test_alias.fi_wt_3months
https://model-catalog.brainsimulation.eu/#test_alias.fi_wt_8months
https://model-catalog.brainsimulation.eu/#test_alias.fi_tg_3months
https://model-catalog.brainsimulation.eu/#test_alias.fi_tg_8months
Model Catalog Entry (for model):
https://model-catalog.brainsimulation.eu/#model_alias.ventral_CA1_pyramidal_neuron_ADmice
(see 4 new model instances; ignore first instance)
Sample Notebook:
https://lab.ch.ebrains.eu/hub/user-redirect/lab/tree/shared/Shailesh-Testing/testting2_july2022/Tests_VF.ipynb
Comments:
Scoring metric can be given more thought and improved if required.