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@danieeeld2 danieeeld2 commented May 21, 2025

  • example 1: Gene Expression
  • example 2: Alveolar Macrophages
  • example 3: Drug Sensitivity

This dataset contains gene expression levels of two genes and their correlation with cancer presence.
@danieeeld2 danieeeld2 added this to the VASCA pipeline in R milestone May 21, 2025
@danieeeld2 danieeeld2 self-assigned this May 21, 2025
@danieeeld2 danieeeld2 added the examples Related with execution examples of pipeline label May 21, 2025
danieeeld2 added 10 commits May 21, 2025 10:41
The script ilustrates how to read the data, generate X and F matrices and how to call vasca pipeline
Added plots and tables generated from the Gene Expression Analysis script
area_under_conc_curve file contains information on the AUC (Area Under the Curve), which, in the context of drug sensitivity assays, refers to the area under the concentration-response curve of a drug in a specific cell line. The other file has metadata information
The script ilustrates how to read the data, generate X and F matrices and how to call vasca pipeline
Added plots and tables generated from the Sensitivity Analysis script
This dataset contains gene expression data from alveolar macrophages2 of smokers and non-smokers
The script ilustrates how to read the data, generate X and F matrices and how to call vasca pipeline
Added plots and tables generated from the Alveolar Macrophages  Analysis script
@danieeeld2 danieeeld2 requested a review from Copilot May 21, 2025 09:06
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Pull Request Overview

This PR introduces new execution examples for three different datasets along with updated CSV result files for various analyses and corresponding R scripts. Key changes include:

  • Addition of new example R scripts (example1.R, example2.R, example2b.R, example3.R) for gene expression, alveolar macrophages, and drug sensitivity.
  • Updates to CSV result files and the inclusion of an expanded cell line info dataset.
  • README updates to reference the new examples folder.

Reviewed Changes

Copilot reviewed 23 out of 23 changed files in this pull request and generated 2 comments.

Show a summary per file
File Description
examples/gene_expression_results/TVS.csv New CSV results for gene expression analysis.
examples/example1.R New example for gene expression analysis via R.
examples/example2.R New example for drug sensitivity analysis with design matrix.
examples/example2b.R Auxiliary script to generate plots with labels.
examples/example3.R New example showing alveolar macrophages analysis in R.
examples/cancer_drug_embryonic_results/TVS.csv New CSV results for cancer drug embryonic analysis.
examples/COPD_tabaco_analysis_results/TVS.csv New CSV results for COPD tobacco analysis.
datasets/v10.M2.cell_line_info.txt Inclusion of updated cell line info dataset.
README.md Updated documentation to include the examples folder reference.
Comments suppressed due to low confidence (1)

examples/example2.R:84

  • [nitpick] The variable name 'F_design_matrix_embrionario' is inconsistent; consider renaming it to 'F_design_matrix_embryonic' for clarity and uniformity.
F_design_matrix_embrionario <- data.frame(

@danieeeld2 danieeeld2 merged commit 150bf4b into main May 21, 2025
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2 participants